Autoimmune Diseases of the Innate and Adaptive Immune System including Atopic Dermatitis, Psoriasis, Chronic Arthritis, Lyme Disease, and Alzheimers Disease

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منابع مشابه

Autoimmune Diseases of the Innate and Adaptive Immune System including Atopic Dermatitis, Psoriasis, Chronic Arthritis, Lyme Disease, and Alzheimer’s Disease

Atopic dermatitis, psoriasis, and chronic arthritis have long been considered autoimmune diseases. Alzheimer’s disease and Lyme disease, however, have not been thought of in that light. In this work, we hope to elucidate how the innate and the adaptive immune systems interact with each disease to produce the familiar symptoms and signs of that disorder. Hopefully, this will provide a framework ...

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Modifications of the innate immune system in atopic dermatitis.

Atopic dermatitis (AD) is a frequent chronic inflammatory skin disease which is often complicated by recurrent microbial superinfections. Genetically based modifications which might have an impact on the innate immune system, such as impairment of the skin barrier, modifications of pattern recognition receptors, deficiency of antimicrobial peptides, antiviral natural killer cells and plasmacyto...

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The genetics of psoriasis, psoriatic arthritis and atopic dermatitis.

Psoriasis and atopic dermatitis are chronic and relapsing inflammatory diseases of the skin associated with various immunologic abnormalities. Approximately 30% of psoriasis patients also have joint involvement, indicative of psoriatic arthritis. Genes and environment play a key role in the pathogenesis of these diseases. Genome-wide linkage scans have identified multiple loci linked to each di...

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Psoriasis and Atopic Dermatitis

Psoriasis and atopic dermatitis are common, chronic inflammatory skin diseases. We discuss several aspects of these disorders, including: risk factors; incidence and prevalence; the complex disease burden; and the comorbidities that increase the clinical significance of each disorder. We also focus on treatment management strategies and outline why individualized, patient-centered treatment reg...

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Little peptide, big effects: the role of LL-37 in inflammation and autoimmune disease.

The innate immune system utilizes many approaches for defense against invading microorganisms, including complement-mediated lysis, engulfment, formation of neutrophil extracellular traps, and release of antimicrobial peptides. Although classically thought to be driven by adaptive immunity, the development of autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus is i...

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ژورنال

عنوان ژورنال: Immunochemistry & Immunopathology

سال: 2015

ISSN: 2469-9756

DOI: 10.4172/2469-9756.1000112